Ophir Klein serves as the inaugural Executive Director of Cedars-Sinai Guerin Children’s and Executive Vice Dean for Children’s Services, and he is the David and Meredith Kaplan Distinguished Chair in Children’s Health. He is a global leader whose team has made seminal contributions to understanding the development of normal and diseased organs, as well as elucidating mechanisms underlying the pathogenesis of complex inherited disorders, many of which manifest during early neonatal and childhood life. He has led the establishment of Guerin Children’s as a respected leader in pediatric scholarly research, training, and specialty clinical services. Dr Klein has received multiple honors, including election to the National Academy of Medicine and the American Association of Physicians. He has had multiple advisory roles to the NIH and led professional societies.

Dr. Klein was educated at the University of California, Berkeley, where he earned a B.A. in Spanish Literature. He subsequently attended Yale University School of Medicine, where he received a Ph.D. in Genetics and an M.D. He then completed residencies at Yale-New Haven Hospital in Pediatrics and at UCSF in Clinical Genetics. Prior to his Cedars-Sinai appointment, Dr Klein served as Chief of Medical Genetics and Craniofacial Anomalies and Director of the Institute for Human Genetics at UCSF.